Thermo Fisher Scientific PPBP Polyclonal Antibody
Thermo Fisher Scientific의 PPBP 폴리클로날 항체는 마우스 단백질을 타깃으로 하며, Western blot과 IHC(P) 분석에 적합합니다. E. coli 유래 NAP2 재조합 단백질로 면역화되어 높은 특이성과 재현성을 제공합니다. 동결건조 형태로 -20°C에서 보관합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived mouse NAP2 recombinant protein (Position: K40–Y113) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 4 mg trehalose |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2746969 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Members of the α-chemokine subfamily of inducible, secreted, pro-inflammatory cytokines contain a conserved Cys-X-Cys motif and are chemotactic for neutrophils. The platelet basic protein (PBP), part of this family, is stored in platelet α-granules and released upon activation. Proteolytic cleavage of PBP generates multiple peptides, including mature PBP, connective tissue-activating peptide III (CTAP III, also known as low-affinity platelet factor IV), β-thromboglobulin (β-TG), and neutrophil-activating peptide 2 (NAP-2). These peptides play roles in inflammation and wound healing, with NAP-2 specifically inducing chemotaxis and degranulation in neutrophils. The human PBP gene is located on chromosome 4q12–q13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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