Thermo Fisher Scientific Heart Fatty Acid Binding Protein (H-FABP)/FABP3 Recombinant Rabbit Monoclonal Antibody (FABP3/8535R)
Human FABP3 단백질에 특이적인 Recombinant Rabbit Monoclonal Antibody로, IHC(P) 및 IHC(PFA) 실험에 적합합니다. 고순도 Protein A/G 정제, PBS 기반 액상 형태이며 보존제 무첨가. 연구용으로 세포 손상 및 지방산 결합 단백질 분석에 활용됩니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | FABP3/8535R |
| Immunogen | Human recombinant FABP3 protein fragment (around aa1–127) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
Fatty acid binding proteins (FABPs) are small (approximately 13–14 kDa) intracellular proteins with high tissue specificity. FABPs bind long-chain fatty acids and play a key role in intracellular fatty acid utilization.
There are at least six distinct types of FABP, each showing specific tissue expression patterns. Due to their small size, FABPs rapidly leak from damaged cells, leading to elevated serum levels.
Liver FABP serves as a sensitive marker for liver cell damage both in vitro and in vivo. Damaged tissues show reduced FABP presence, aiding histological identification. Additionally, L-FABP is useful for detecting rapid hepatocyte lysis in toxicology assays and monitoring liver damage during transplantation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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