Thermo Fisher Scientific Bcl-X (Apoptosis Marker) Monoclonal Antibody (BCL2L1/1762)
Bcl-X 단백질을 인식하는 단클론 항체로, 세포자멸사(Apoptosis) 연구용 마커로 사용됩니다. 인간 시료에 반응하며 ELISA에 적합합니다. 단백질 A/G로 정제된 액상 형태로 제공되며, 보존제가 포함되지 않습니다. -20°C에서 보관합니다.
- 카탈로그번호
- 598-MSM4-P1ABX
- 판매단위
- pk
카탈로그
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Applications
- ELISA (ELISA): 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BCL2L1/1762 |
| Immunogen | Recombinant human BCL2L1 protein fragment (around aa 1–135) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by the BCL-X gene belongs to the BCL-2 protein family. Members of this family form hetero- or homodimers and act as anti- or pro-apoptotic regulators involved in various cellular activities. These proteins are located at the outer mitochondrial membrane and regulate the mitochondrial membrane channel (VDAC) opening. VDAC controls mitochondrial membrane potential, reactive oxygen species production, and cytochrome C release — key factors in apoptosis.
Alternative splicing results in multiple transcript variants encoding two isoforms: the longer isoform acts as an apoptotic inhibitor, while the shorter isoform acts as an apoptotic activator.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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