Thermo Fisher Scientific APOBR Monoclonal Antibody (OTI6A6), TrueMAB
인간 APOBR 단백질(780-1088 aa)을 인식하는 마우스 단클론 항체로 Western blot에 적합. Lyophilized 형태, 1 mg/mL 농도, PBS 및 trehalose 버퍼 포함. 연구용으로만 사용, 재구성 및 탈염 실험에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6A6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 780–1088 of human APOBR produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Macrophage receptor that binds apolipoprotein B48 (APOB) of dietary triglyceride-rich lipoproteins (TRL) or similar domains of APOB in hypertriglyceridemic very low-density lipoprotein (HTG-VLDL).
This receptor binds and internalizes TRL outside the macrophage context, possibly supplying essential lipids to reticuloendothelial cells.
It may also participate in foam cell formation under elevated TRL and remnant lipoprotein (RLP) conditions.
Mediates rapid, high-affinity uptake of chylomicrons (CM), HTG-VLDL, and trypsinized VLDL lacking APOE in vitro in macrophages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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