Thermo Fisher Scientific APOBR Monoclonal Antibody (OTI7A7), TrueMAB
인간 APOBR 단백질(aa 780-1088)을 타겟으로 하는 Mouse IgG1 단일클론 항체. Western blot에 1:2,000 희석으로 검증됨. 무보존제, 동결건조 형태로 제공되며, 연구용으로만 사용 가능.
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Thermo Fisher Scientific APOBR Monoclonal Antibody (OTI7A7), TrueMAB
Applications
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7A7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 780–1088 of human APOBR produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Macrophage receptor that binds to apolipoprotein B48 (APOB) of dietary triglyceride-rich lipoproteins (TRL) or to a similar domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL).
It binds and internalizes TRL outside the macrophage context, possibly supplying essential lipids to reticuloendothelial cells.
May contribute to foam cell formation under elevated TRL and remnant lipoprotein (RLP) conditions.
Mediates rapid, high-affinity uptake of chylomicrons (CM), HTG-VLDL, and trypsinized VLDL devoid of APOE in vitro in macrophages.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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