Thermo Fisher Scientific CD36 Polyclonal Antibody
CD36 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간 및 마우스 시료에 반응합니다. Western blot, IHC, ICC/IF 등 다양한 응용에 적합하며 항원 친화 크로마토그래피로 정제되었습니다. 장기 보관 시 -20°C에서 냉동 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:3,000 | View 3 publications |
| Immunohistochemistry (IHC) | – | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 | – |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | – |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 302–395 of Human CD36 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.47 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2544712 |
Product Specific Information
- Recommended positive controls: K562, mouse brown adipose, RAW264.7
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
CD36, also known as scavenger receptor class B member 3, is expressed on macrophages, platelets, and adipocytes. It plays a role in lipid metabolism, inflammation, and atherosclerosis, and recognizes ligands such as oxidized LDL, long-chain fatty acids, and apoptotic cells.
CD36 acts as a receptor for thrombospondin and is a major glycoprotein on platelet surfaces. It binds collagen, thrombospondin, anionic phospholipids, and oxidized LDL, mediating cytoadherence of Plasmodium falciparum-infected erythrocytes.
Mutations in CD36 cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been identified.
Diseases associated with CD36 include Platelet Glycoprotein IV Deficiency and Coronary Heart Disease 7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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