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Thermo Fisher Scientific Human Gremlin-1 Recombinant Protein, PeproTech
상품 한눈에 보기
Recombinant Human Gremlin-1 단백질로 BMP-4 유도 활성 억제 기능을 검증함. CHO 세포 발현 시스템 사용, ≥90% 순도 확보. 18.3 kDa 크기, 무보존제 동결건조 형태로 제공되며 연구용으로만 사용 가능.
- 카탈로그번호
- 120-42-xxxxx (5개 옵션)
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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마지막 업데이트 2025. 08. 04. 오전 03:04
카탈로그 번호 · 상품 설명출고판매가담기
Thermo Fisher Scientific 120-42-500UG Human Gremlin-1 Recombinant Protein, PeproTech 500 ug pk판매 단위 pk
재고 1개
1,551,300원VAT 포함 1,706,430원
Thermo Fisher Scientific 120-42-250UG Human Gremlin-1 Recombinant Protein, PeproTech 250 ug pk판매 단위 pk
재고 1개
968,800원VAT 포함 1,065,680원
Thermo Fisher Scientific 120-42-100UG Human Gremlin-1 Recombinant Protein, PeproTech 100 ug pk판매 단위 pk ·
재고 확인 필요
621,700원VAT 포함 683,870원
Thermo Fisher Scientific 120-42-50UG Human Gremlin-1 Recombinant Protein, PeproTech 50 ug pk판매 단위 pk ·
재고 확인 필요
312,800원VAT 포함 344,080원
Thermo Fisher Scientific 120-42-10UG Human Gremlin-1 Recombinant Protein, PeproTech 10 ug pk판매 단위 pk ·
재고 확인 필요
139,800원VAT 포함 153,780원
Thermo Fisher Scientific · Thermo Fisher Scientific Human Gremlin-1 Recombinant Protein, PeproTech
Applications
Functional Assay (Functional)
- Assay-dependent
In vitro Assay (IV)
- View 3 publications
Miscellaneous PubMed (Misc)
- View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Published Species | Cat, Human, Mouse |
| Expression System | CHO cells |
| Amino Acid Sequence | KKKGSQGAIP PPDKAQHNDS EQTQSPQQPG SRNRGRGQGR GTAMPGEEVL ESSQEALHVT ERKYLKRDWC KTQPLKQTIH EEGCNSRTII NRFCYGQCNS FYIPRHIRKE EGSFQSCSFC KPKKFTTMMV TLNCPELQPP TKKKRVTRVK QCRCISIDLD |
| Molecular Weight | 18.3 kDa |
| Class | Recombinant |
| Type | Protein |
| Purity | ≥ 90% by SDS-PAGE gel and HPLC analyses |
| Endotoxin Concentration | <1 EU/µg |
| Activity | Inhibits BMP-4 induced alkaline phosphatase production by ATDC-5 chondrogenic cells. ED50: 0.07–0.11 µg/ml |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | Purified |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient |
Product Specific Information
- Catalog No. 120-42-1MG is supplied as 2 × 500 µg (120-42-500UG).
- Recombinant Human Gremlin-1 is a 18.3 kDa protein containing 160 amino acid residues.
- Shipped at ambient temperature.
- For storage, handling, and reconstitution information, refer to the lot-specific Certificate of Analysis.
Target Information
In Xenopus, Gremlin belongs to a novel gene family that acts as BMP antagonists in embryonic explants.
The human homolog of Drm/Gremlin (CKTFS1B1) is localized on chromosome 15q13–q15.
DRM-specific mRNA is expressed in human tissues including brain, ovary, intestine, and colon.
Down-regulation of DRM is associated with tumor progression, suggesting that human DRM may play a role in neuroembryological development and carcinogenesis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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