Thermo Fisher Scientific Phospho-CK1 alpha (Thr321) Polyclonal Antibody
Phospho-CK1 alpha (Thr321) 폴리클로날 항체로, 인산화된 CK1α 단백질을 특이적으로 검출. Western blot에 적합하며 Human, Mouse, Rat 시료 반응. 1 mg/mL 액상 형태, PBS/glycerol buffer에 보관. 연구용으로만 사용 가능.
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- PA5105061
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CSNK1A1 (Accession P48729), corresponding to amino acid residues around phosphorylated Thr321 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816534 |
Product Specific Information
This antibody detects endogenous levels of Casein Kinase 1 alpha only when phosphorylated at Thr321.
Target Information
CNSK1A1 (CK1 alpha 1) is a member of the casein kinase I (CKI) gene family, which encodes serine/threonine kinases that preferentially phosphorylate acidic substrates. CKI proteins are monomeric (25–55 kDa) and are found in the nuclei, cytoplasm, and membrane fractions of eukaryotic cells.
It can phosphorylate a large number of proteins and participates in Wnt signaling. It phosphorylates CTNNB1 at Ser-45 and may phosphorylate PER1 and PER2. It may also play a role in chromosome segregation during mitosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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