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Thermo Fisher Scientific Phospho-MPRIP (Thr542) Polyclonal Antibody
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Thermo Fisher Scientific Phospho-MPRIP (Thr542) Polyclonal Antibody

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인산화된 Thr542 부위의 MPRIP 단백질을 특이적으로 검출하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. Human, Mouse, Rat 시료에서 반응하며 액상 형태로 제공됩니다. 세포골격 조절 연구에 유용한 연구용 항체입니다.

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PA5105059
판매단위
pk
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마지막 업데이트 2025. 08. 02. 오전 01:44
Thermo Fisher Scientific PA5105059 Phospho-MPRIP (Thr542) Polyclonal Antibody 100 ul pk판매 단위 pk ·
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627,600원VAT 포함 690,360원

Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-MPRIP (Thr542) Polyclonal Antibody

Applications

Western Blot (WB)

  • Tested Dilution: 1:500–1:2,000

Product Specifications

항목 내용
Species Reactivity Human, Mouse, Rat
Host/Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen A synthesized peptide derived from human MPRIP (Accession Q6WCQ1), corresponding to amino acid residues around phosphorylated Thr542
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Sequential chromatography
Storage Buffer PBS, pH 7.4, with 50% glycerol
Contains 0.02% sodium azide
Storage Conditions -20°C
Shipping Conditions Wet ice
RRID AB_2816532

Product Specific Information

Antibody detects endogenous levels of MRIP only when phosphorylated at Thr542.


Target Information

MPRIP targets myosin phosphatase to the actin cytoskeleton and is required for regulation of the actin cytoskeleton by RhoA and ROCK1.
Depletion leads to increased stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin.
Overexpression of MRIP or its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.


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