Thermo Fisher Scientific PSA Recombinant Rabbit Monoclonal Antibody (4H23L24)

Applications

• Western Blot (WB): 1–2 µg/mL
• Immunocytochemistry (ICC/IF): 2 µg/mL

Product Specifications

Product Specific Information

This antibody is predicted to react with Monkey, Rabbit, Pig, Bovine, and Rat.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning the antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.

Advantages:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broader immunoreactivity to diverse targets due to large rabbit immune repertoire

Target Information

PSA (Prostate-Specific Antigen) is a chymotrypsin-like serine protease of the kallikrein family produced by the prostate epithelium and abundant in seminal fluid. It can be detected in sera of patients with prostatic carcinoma. PSA is predominantly complexed with alpha-1-antichymotrypsin (ACT), a liver-derived serine protease inhibitor. The proportion of PSA complexed to ACT is higher in prostate cancer than in benign prostatic hyperplasia.
PSA is used to confirm prostatic acinar cell origin in primary and metastatic carcinoma and to rule out non-prostatic carcinoma mimics.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.