Thermo Fisher Scientific Nkx2.5 Recombinant Rabbit Monoclonal Antibody (4H5L9)
Recombinant rabbit monoclonal antibody recognizing human Nkx2.5. Provides high specificity and sensitivity for ICC/IF applications. Offers lot-to-lot consistency and animal-origin-free formulation. Suitable for heart development and transcription facto...
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
- View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 4H5L9 |
| Immunogen | Human Nkx2.5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2532496 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.
Advantages:
- Improved specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to rabbit immune repertoire
Target Information
The Nkx2.5 gene encodes a homeobox-containing transcription factor involved in heart formation and development.
Mutations in this gene can cause:
- Atrial septal defect with atrioventricular conduction defect
- Tetralogy of Fallot (heart malformation)
- Congenital hypothyroidism non-goitrous type 5 (non-autoimmune)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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