Thermo Fisher Scientific CD44v10 Monoclonal Antibody (VFF-14)
인간 CD44v10 항원을 인식하는 Mouse IgG1 단클론 항체로, FACS 및 Western blot에 사용 가능. 1 mg/mL 농도의 액상 형태로 제공되며 PBS 버퍼에 보존제 없이 저장. 세포 표면 CD44 분석 및 암 관련 연구에 적합.
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Applications
Western Blot (WB)
- Assay-dependent
Flow Cytometry (Flow)
- Assay-dependent
Miscellaneous PubMed (Misc)
- View 1 publication (PubMed)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | VFF-14 |
| Immunogen | Proprietary |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Purified |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538437 |
Product Specific Information
For FACS analysis, use 10 µL of the suggested working dilution to label 1×10^6 cells in 100 µL.
Target Information
CD44 cell surface antigen is a 100 kDa glycoprotein widely expressed on human leukocytes, white matter of the brain, and some epithelial cells of the intestine and breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues.
CD44 acts as a receptor for hyaluronic acid (HA) and plays roles in cell-cell interactions, adhesion, and migration. It is also involved in lymphocyte activation, recirculation, and homing.
CD44 expression may be up-regulated in certain carcinomas and is speculated to be related to metastatic potential.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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