Thermo Fisher Scientific CD44v6 Monoclonal Antibody (VFF-7), FITC
CD44v6 단백질을 인식하는 FITC 결합 단일클론 항체로, 인간 세포 표면 CD44 검출에 적합. Flow Cytometry(FACS) 분석용으로 최적화. 고순도 친화 크로마토그래피 정제. 단기 4°C, 장기 -20°C 보관 권장.
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Thermo Fisher Scientific CD44v6 Monoclonal Antibody (VFF-7), FITC
Applications
- Flow Cytometry (Flow)
Tested Dilution: Neat
Publications: View 2 publications
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | VFF-7 |
| Immunogen | Glutathione S Transferase (GST) fusion protein corresponding to the variable domains (v3 to v10) of human CD44 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | TBS with 1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538440 |
Product Specific Information
For FACS analysis, use 10 µL of the suggested working dilution to label 1×10⁶ cells in 100 µL.
Target Information
CD44 cell surface antigen is a 100 kDa glycoprotein widely expressed on human leukocytes, white matter of the brain, and some epithelial cells of the intestine and breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues.
CD44 acts as a receptor for hyaluronic acid (HA) and is involved in cell–cell interactions, adhesion, and migration. It participates in lymphocyte activation, recirculation, and homing. CD44 expression may be up-regulated in some carcinomas and may be related to metastatic potential.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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