Thermo Fisher Scientific Hepatitis B Virus Core Antigen Monoclonal Antibody (1-5)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunohistochemistry (IHC)

Assay-dependent

View 1 publication 1 publication

Immunocytochemistry (ICC/IF)

-

View 1 publication 1 publication

Flow Cytometry (Flow)

-

View 2 publications 2 publications

ELISA (ELISA)

1:500

-

Immunoprecipitation (IP)

Assay-dependent

View 2 publications 2 publications

Product Specifications

Species Reactivity

Virus

Published species

Virus

Host/Isotype

Mouse / IgG2b

Class

Monoclonal

Type

Antibody

Clone

1-5

Immunogen

Purified recombinant HBcAg.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.0 mg/mL

Storage buffer

PBS, pH 7.2

Contains

no preservative

Storage conditions

4°C short term, -80°C long term

RRID

AB_1075044

Product Specific Information

MA1-7607 detects HBcAg from virus samples.

MA1-7607 has been successfully used in Western blot, ELISA, immunoprecipitation and immunohistochemistry procedures.

The MA1-7607 immunogen is a purified recombinant HBcAg core protein. The epitope corresponds to residues surrounding residue 80.

Store at 4ºC short term, and -80ºC long term.

Target Information

The hepatitis B virus is an important cause of acute and chronic liver disease. It is also the most common form of parenterally transmitted viral hepatitis. Hepatitis B virus is spherical in shape with a diameter of 42nm. It contains a 27 nm partially double stranded DNA core enclosed within a lipoprotein coat. The antigenic activity of the nucleocapsid core is designated as hepatitis B core antigen. The antigens in the outer surface are called as hepatitis B virus surface antigens. Core antigens are localized within the nuclei whereas the surface antigens are present in the cytoplasm of the infected cells. Antibodies to surface antigens appear in circulation at an early stage of infection whereas the antibodies to the core antigens are detected after several weeks. The virus is estimated to affect some 350 million people worldwide. Immunization against hepatitis B is an important component of preventative medicine and is offered to all children in approximately 30 countries. Hepatitis B virus (HBV) belongs to the Hepadnaviridae family and infection with HBV is usually more serious than infection with hepatitis A virus. In some individuals the infection is not cleared and followed by persistent intracellular viral carriage that can lead to the development of hepatocelular carcinomas. There are currently 400 million HBV carriers worldwide making HBV one of the most common human pathogens.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.