
Thermo Fisher Scientific SARS-CoV-2 Spike Protein S1 Polyclonal Antibody
SARS-CoV-2 Spike Protein S1을 인식하는 토끼 폴리클로날 항체로, WB, ICC/IF, ELISA에 사용 가능. SARS-CoV 및 MERS-CoV 스파이크 단백질과 교차 반응하지 않음. 연구용으로만 사용되며 고감도 검출에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:10,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of SARS-CoV-2 Spike (S1). The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2890591 |
Product Specific Information
This antibody detects SARS-CoV-2 Spike protein, but does not cross-react with SARS-CoV or MERS-CoV spike proteins based on internal testing.
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV (2019 Novel Coronavirus), causes illnesses ranging from mild cold-like symptoms to severe respiratory distress and death.
The SARS-CoV-2 Spike Protein consists of S1 and S2 domains. It is the main surface antigen of the virus. The glycosylated Spike protein can be detected in infected cell culture supernatants using antisera from SARS patients.
The S1 domain contains a receptor-binding domain (RBD) that specifically binds to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells. CoV diversity is reflected in variations of Spike proteins, which differ in receptor interactions and responses to environmental triggers of virus-cell membrane fusion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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