Thermo Fisher Scientific TMEM173 Monoclonal Antibody (OTI4H8), TrueMAB
TMEM173(STING) 단백질을 인식하는 Mouse monoclonal antibody로 Western blot 및 IHC(P) 검증됨. Lyophilized 형태이며 PBS buffer에 trehalose 포함. Human 시료 반응, carrier-free로 conjugation 실험에 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4H8 |
| Immunogen | Full length human recombinant TMEM173 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
STING (TMEM173) is a 379 amino acid signaling protein essential for innate immune signaling. It activates NF-κB and IRF3 pathways to induce type I interferons (IFN-α and IFN-β), promoting antiviral responses.
STING is associated with the endoplasmic reticulum, cell membrane, and mitochondrial outer membrane, and is ubiquitously expressed in most tissues. It may also mediate apoptotic signaling through interactions with MHC-II and ERK pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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