Thermo Fisher Scientific TMEM173 Monoclonal Antibody (OTI3B10), TrueMAB

Applications and Tested Dilutions

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

STING is a 379-amino-acid signaling protein that plays a key role in innate immune signaling. It activates NF-kappa-B and IRF3 transcription pathways, leading to type I interferon (IFN-α and IFN-β) expression and antiviral responses.
STING may also function as a translocon influencing interferon induction and mediates apoptotic signaling through MHC-II association. It is localized in the endoplasmic reticulum membrane, cell membrane, and mitochondrial outer membrane, and is ubiquitously expressed in most tissues.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.