
Thermo Fisher Scientific TMEM173 Monoclonal Antibody (OTI4A7), TrueMAB
인간 TMEM173(STING)에 특이적인 단클론 항체로, Western blot에 최적화됨. HEK293T 세포에서 생산된 재조합 단백질을 면역원으로 사용. 동결건조 형태로 제공되며, 보존제가 없는 PBS/trehalose buffer에 용해 가능. 연구용으로만 사용 가능.
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Thermo Fisher Scientific TMEM173 Monoclonal Antibody (OTI4A7), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution
- 1:200–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4A7 |
| Immunogen | Full-length human recombinant protein of TMEM173 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
STING is a 379-amino-acid signaling protein involved in innate immune response activation. It triggers NF-κB and IRF3 pathways, leading to type I interferon (IFN-α, IFN-β) expression and antiviral defense.
STING may also function as a translocon influencing interferon induction, and participates in apoptotic signal transduction via MHC-II interaction.
It localizes to the endoplasmic reticulum, cell membrane, and mitochondrial outer membrane, and is ubiquitously expressed across tissues.
Usage Notice
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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