Thermo Fisher Scientific SLC6A15 Polyclonal Antibody
SLC6A15 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. Western blot, IHC, ICC/IF에 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 인간 시료에 반응하며, 장기 보관은 -20°C에서 권장됩니다.
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- PA552586
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SLC6A15 (Recombinant protein control fragment Product #RP-89570) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647547 |
Product Specific Information
Immunogen sequence:
RELDDDVTES VKDLLSNEDA ADDAFKTSEL IVDGQEEKDT DVEEGSEVED ERPAWNSKLQ
Highest antigen sequence identity to the following orthologs:
- Mouse: 77%
- Rat: 80%
Target Information
SLC6A15 (solute carrier family 6 (neutral amino acid transporter), member 15), also known as sodium-dependent neutral amino acid transporter B(0)AT2, transporter v7-3, NTT73, or sodium-coupled branched-chain amino-acid transporter 1 (SBAT1), is a 730 amino acid multi-pass membrane protein that acts as a sodium-dependent neutral amino acid transporter.
It belongs to the sodium neurotransmitter symporter (SNF) family and SLC6A15 subfamily, differing from other members in that it is not chloride-dependent. SLC6A15 is expressed in the brain and is encoded by a gene located on human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome.
Chromosome 12 is associated with various diseases and conditions including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome, and trisomy 12p, which causes facial developmental defects and seizure disorders.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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