Thermo Fisher Scientific AKAP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human AKAP1 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:AKAP1,uniProtId:Q92667-1,ncbiNodeId:9606,antigenRange:223-363,antigenLength:903,antigenImageFileName:PA5-52589_AKAP1_Q92667-1_Rabbit.svg,antigenImageFileNamePDP:PA5-52589_AKAP1_Q92667-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2637801

Product Specific Information

Immunogen sequence: EHVLELENSK GPSLASLEGE EDKGKSSSSQ VVGPVQEEEY VAEKLPSRFI ESAHTELAKD DAAPAPPVAD AKAQDRGVEG ELGNEESLDR NEEGLDRNEE GLDRNEESLD RNEEGLDRNE EIKRAAFQII SQVISEATEQ V

Highest antigen sequence identity to the following orthologs: Mouse - 35%, Rat - 35%.

Target Information

This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.