Thermo Fisher Scientific CD9 Monoclonal Antibody (5G6)

Applications and Tested Dilution

Product Specifications

Product Specific Information

MA5-17049 targets CD9 in FACS, IHC, indirect ELISA, and WB applications and shows reactivity with human samples.
The immunogen is a synthesized peptide of human CD9.
MA5-17049 detects CD9, which has a predicted molecular weight of approximately 25 kDa.

Target Information

CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophils, stimulated T lymphocytes, and by neurons and glial cells in the peripheral nervous system.
It belongs to the tetraspanin family, which spans the membrane four times. In pre-B cells and platelets, CD9 regulates cell activation and aggregation, possibly through association with integrin CD41/CD61 (GPIIb/GPIIIa).
CD9 is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion. It plays roles in cell attachment and proliferation and is necessary for association of heterologous MHC II molecules on dendritic cell membranes, important for effective T cell stimulation.
CD9 functions in differentiation, adhesion, and signal transduction, and its expression plays a critical role in suppression of cancer cell motility and metastasis. It is considered a metastasis suppressor in solid tumors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.