Thermo Fisher Scientific Synaptophysin Polyclonal Antibody
Synaptophysin 단백질을 검출하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC 등 다양한 응용 가능. 여러 종(인간, 생쥐, 쥐, 소, 양)에 반응. 항원 친화 크로마토그래피로 정제된 액상 형태, 안정적 저장(-20°C).
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- PA11043
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- pk
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 7 publications |
| Immunohistochemistry (IHC) | - | View 7 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 10 µg/mL | - |
| Immunocytochemistry (ICC/IF) | Assay-dependent | View 4 publications |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Bovine, Human, Mouse, Sheep, Rat |
| Published Species | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues G(253)–D(272) of rat Synaptophysin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2199026 |
Product Specific Information
PA1-1043 detects Synaptophysin in rat, mouse, bovine, and sheep samples.
It has been successfully used in Western blot and immunofluorescence procedures.
By Western blot, this antibody detects a ~33.8 kDa protein representing Synaptophysin in rat, mouse, and bovine brain tissue as well as sheep retinas.
The PA1-1043 immunogen is a synthetic peptide corresponding to residues G(253)–D(272) of rat Synaptophysin.
This sequence is conserved in many species including human, mouse, and bovine.
The immunizing peptide (Cat. # PEP-279) is available for use in neutralization and control experiments.
Target Information
Synaptophysin is a calcium-binding integral membrane glycoprotein present in presynaptic vesicles of nearly all neurons.
It has four transmembrane domains and forms a complex with dynamin at high calcium concentrations, suggesting involvement in synaptic vesicle endocytosis.
It also contributes to the regulation of short-term and long-term synaptic plasticity.
Synaptophysin is widely used as a marker for nerve terminals and for differentiating neuroendocrine tumors.
Mutations in the gene can result in mental retardation (X-linked 96).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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