Thermo Fisher Scientific EZR Monoclonal Antibody (OTI1F3), TrueMAB
EZR 단백질을 인식하는 마우스 단클론 항체로, Western Blot 및 Immunocytochemistry에 사용 가능. 인간 단백질에 반응하며, 정제된 동결건조 형태로 제공. 세포막-세포골격 상호작용 연구 및 암 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F3 |
| Immunogen | Full length human recombinant protein of human EZR produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli.
As a member of the ERM protein family, it acts as an intermediate between the plasma membrane and the actin cytoskeleton.
This protein is crucial for cell surface structure adhesion, migration, and organization, and has been implicated in various human cancers.
A pseudogene located on chromosome 3 has been identified, and alternatively spliced variants have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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