Thermo Fisher Scientific ALOX5 Monoclonal Antibody (OTI2D7), TrueMAB
ALOX5 단백질을 인식하는 Mouse monoclonal antibody로, Western blot에 최적화되어 있습니다. Human 시료에 반응하며, 무보존제 동결건조 제형으로 제공됩니다. 재구성 후 1 mg/mL 농도로 사용 가능하며, 연구용으로 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 18–364 of human ALOX5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
This gene encodes a protein that, together with Arachidonate 5-lipoxygenase-activating protein, is required for leukotriene synthesis.
Leukotrienes are arachidonic acid metabolites implicated in inflammatory responses such as asthma, arthritis, and psoriasis.
This protein localizes to the plasma membrane. Inhibitors of its function impede the translocation of 5-lipoxygenase from the cytoplasm to the cell membrane, thus inhibiting 5-lipoxygenase activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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