Thermo Fisher Scientific ALOX5 Monoclonal Antibody (OTI3F1), TrueMAB
ALOX5 단백질을 인식하는 Mouse monoclonal antibody로, Western blot 및 IHC(P) 실험에 적합. Human에 반응하며 carrier-free 형태로 제공. 연구용으로 leukotriene 합성 관련 연구에 활용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3F1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 18–364 of human ALOX5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional round of desalting (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
ALOX5 encodes a protein that, together with Arachidonate 5-lipoxygenase-activating protein, is required for leukotriene synthesis.
Leukotrienes are arachidonic acid metabolites implicated in inflammatory responses such as asthma, arthritis, and psoriasis.
This protein localizes to the plasma membrane. Inhibitors of its function prevent translocation of 5-lipoxygenase from the cytoplasm to the membrane, thereby inhibiting its activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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