Thermo Fisher Scientific ALOX5 Monoclonal Antibody (OTI2B7), TrueMAB
Human ALOX5 단백질(aa 18-364)에 특이적인 Mouse monoclonal antibody. Western blot에 적합하며, carrier-free 형태로 제공. 동결건조 상태로 공급되며, 재구성 후 1 mg/mL 농도. 염증 반응 관련 연구에 유용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B7 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 18–364 of human ALOX5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The ALOX5 gene encodes a protein that, together with Arachidonate 5-lipoxygenase-activating protein, is essential for leukotriene synthesis.
Leukotrienes are arachidonic acid metabolites involved in inflammatory responses such as asthma, arthritis, and psoriasis.
This protein localizes to the plasma membrane. Inhibitors of ALOX5 function prevent translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit its activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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