Thermo Fisher Scientific NME1 Monoclonal Antibody (OTI18C12), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

NME1 is characterized by reduced mRNA transcript levels in highly metastatic cells.
Nucleoside diphosphate kinase (NDK) forms a hexamer composed of A (encoded by NME1) and B (encoded by NME2) isoforms.
Mutations in NME1 are associated with aggressive neuroblastomas.
Two transcript variants encoding different isoforms have been identified.
Co-transcription with the downstream NME2 gene produces naturally occurring NME1-NME2 fusion transcripts, encoding a protein with shared sequence identity from both genes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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