Thermo Fisher Scientific Carboxypeptidase A1 Monoclonal Antibody (CL6629)
Carboxypeptidase A1 단백질을 인식하는 CL6629 단일클론 항체. Western blot 및 IHC(파라핀 절편)에서 검증됨. Human 시료에 반응하며, Protein A로 정제된 1 mg/mL 액상 제품. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:5,000–1:10,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL6629 |
| Immunogen | Recombinant protein corresponding to Human CPA1 (amino acids 19–88, total length 419 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2787077 |
Product Specific Information
Immunogen sequence:
DFVGHQVLRI SVADEAQVQK VKELEDLEHL QLDFWRGPAH PGSPIDVRVP FPSIQAVKIF LESHGISYET
Target Information
Protein: CPA1 (Carboxypeptidase A1)
Description: CPA1, also known as CPA, is a 419 amino acid secreted monomeric protein highly expressed in pancreatic tissue. It functions as a pancreatic exopeptidase using zinc as a cofactor to catalyze the release of C-terminal amino acids from various proteins, playing a key role in protein digestion and degradation. CPA1 is also thought to participate in zymogen inhibition, potentially regulating enzyme activation pathways. Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting roles in tumor progression or suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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