Thermo Fisher Scientific Carboxypeptidase A1 Monoclonal Antibody (CL6629)

Applications

Tested Dilution

Publications

Western Blot (WB)

1 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:5,000-1:10,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

CL6629

Immunogen

Recombinant protein corresponding to Human CPA1 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Carboxypeptidase A1,uniProtId:P15085-1,ncbiNodeId:9606,antigenRange:19-88,antigenLength:419,antigenImageFileName:MA5-31441_Carboxypeptidase_A1_P15085-1_House_mouse.svg,antigenImageFileNamePDP:MA5-31441_Carboxypeptidase_A1_P15085-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2787077

Product Specific Information

Immunogen sequence: DFVGHQVLRI SVADEAQVQK VKELEDLEHL QLDFWRGPAH PGSPIDVRVP FPSIQAVKIF LESHGISYET

Target Information

CPA1, also known as CPA, is a 419 amino acid secreted monomeric protein that is highly expressed in pancreatic tissue. Functioning as a pancreatic exopeptidase, CPA1 uses zinc as a cofactor to catalyze the release of C-terminal amino acids from a variety of proteins, thereby playing a key role in protein digestion and degradation. Via its catalytic activity, CPA1 is also thought to be involved in zymogen (proenzyme) inhibition, probably functioning to block enzyme activation pathways. Abnormal levels of CPA1 are associated with pancreatic cancer, suggesting a possible role in either tumor progression or tumor suppression events.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.