Thermo Fisher Scientific Calreticulin Recombinant Rabbit Monoclonal Antibody (SU37-03)
Calreticulin 단백질을 인식하는 재조합 토끼 단클론 항체로, Western blot, IHC, Flow Cytometry에 적합합니다. 높은 특이성과 민감도를 제공하며, 로트 간 일관성이 우수합니다. 단백질 A로 정제된 액상 항체로, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:5,000–1:50,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 | - |
| Flow Cytometry (Flow) | 1:2,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SU37-03 |
| Immunogen | Synthetic peptide within Human Calreticulin (aa 40–89) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% Sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809422 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning the specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages of recombinant rabbit monoclonal antibodies:
- High specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to the large rabbit immune repertoire
Target Information
Calr (Calreticulin) is a calcium-binding chaperone that promotes folding, oligomeric assembly, and quality control in the endoplasmic reticulum (ER) via the calreticulin/calnexin cycle. It interacts transiently with monoglucosylated glycoproteins synthesized in the ER and with the DNA-binding domain of NR3C1 to mediate nuclear export. Calreticulin may also be involved in maternal gene expression regulation and oocyte maturation through calcium homeostasis regulation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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