Thermo Fisher Scientific IL6R Polyclonal Antibody
IL6R 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot, IHC, ELISA에 적합합니다. 인간, 마우스, 랫트 시료에 반응하며, 고순도의 Affinity Chromatography 정제 제품입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein corresponding to amino acids 20–365 of human IL6R (NP_000556.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.17 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855266 |
Product Specific Information
Immunogen sequence:
LAPRRCPAQE VARGVLTSLP GDSVTLTCPG VEPEDNATVH WVLRKPAAGS HPSRWAGMGR RLLLRSVQLH DSGNYSCYRA GRPAGTVHLL VDVPPEEPQL SCFRKSPLSN VVCEWGPRST PSLTTKAVLL VRKFQNSPAE DFQEPCQYSQ ESQKFSCQLA VPEGDSSFYI VSMCVASSVG SKFSKTQTFQ GCGILQPDPP ANITVTAVAR NPRWLSVTWQ DPHSWNSSFY RLRFELRYRA ERSKTFTTWM VKDLQHHCVI HDAWSGLRHV VQLRAQEEFG QGEWSEWSPE AMGTPWTESR SPPAENEVST PMQALTTNKD DDNILFRDSA NATSLPVQDS SSVPLP
Target Information
Interleukin 6 receptor (IL6R), also known as CD126 (Cluster of Differentiation 126), is a type I cytokine receptor. This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. IL6 regulates cell growth and differentiation and plays a crucial role in immune response. The IL6 receptor complex includes IL6R and the interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), shared by many cytokines. Dysregulated IL6/IL6R expression is associated with diseases such as multiple myeloma, autoimmune disorders, and prostate cancer. Alternatively spliced variants and a pseudogene on chromosome 9 have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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