Thermo Fisher Scientific IL24 Polyclonal Antibody
IL24 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ELISA 등에 사용 가능. Mouse 및 Rat 반응성. 고순도 Affinity Chromatography 정제, 안정적인 PBS/glycerol buffer 포맷. 연구용으로 JAK/STAT 신호 관련 연구에 적합.
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Thermo Fisher Scientific IL24 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| ELISA | 1 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 52–140 of human IL24 (NP_001172085.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.06 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855265 |
Product Specific Information
Immunogen sequence:
GQEFHFGPCQ VKGVVPQKLW EAFWAVKDTM QAQDNITSAR LLQQEVLQNV SDAESCYLVH TLLEFYLKTV FKNYHNRTVE VRTLKSFST
Target Information
Interleukin 24 (IL-24), also known as melanoma differentiation-associated gene-7 (mda-7), encodes a secreted protein homologous to the interleukin 10 (IL-10) family of cytokines.
Human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2, activating JAK/STAT signaling pathways.
Mda-7/IL-24 selectively induces growth suppression, apoptosis, and radiosensitization in malignant gliomas in a p53-independent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-109854_IL24_Q13007-1_Rabbit.svg, PA5-109854_IL24_Q13007-1_Rabbit_PDP.jpeg)
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