Thermo Fisher Scientific ING3 Polyclonal Antibody
ING3 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 ELISA에 최적화됨. Human, Mouse, Rat 시료에 반응하며, 고순도의 Affinity Chromatography로 정제됨. PBS/glycerol buffer에 보관되며 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1–92 of human ING3 (NP_938008.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855268 |
Product Specific Information
Immunogen sequence:
MLYLEDYLEM IEQLPMDLRD RFTEMREMDL QVQNAMDQLE QRVSEFFMNA KKNKPEWREE QMASIKKDYY KALEDADEKV QLANQIYDLQ HFTarget Information
The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger motif, commonly found in proteins involved in chromatin remodeling. It can activate p53 trans-activated promoters, including those of p21/waf1 and bax. Overexpression of this gene inhibits cell growth and induces apoptosis. Allelic loss and reduced expression have been detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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