Thermo Fisher Scientific GP130 Polyclonal Antibody
Thermo Fisher Scientific의 GP130 Polyclonal Antibody는 인간 IL6ST 단백질을 인식하는 Rabbit IgG 항체로, WB, IHC, ICC/IF에 사용 가능. 액상 형태로 제공되며 -20°C에서 보관. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 678–857 of human IL6ST (NP_001177910.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.58 mg/mL |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855267 |
Product Specific Information
Sequence of this protein is as follows:
PSISSSDENE SSQNTSSTVQ YSTVVHSGYR HQVPSVQVFS RSESTQPLLD SEERPEDLQL VDHVDGGDGI LPRQQYFKQN CSQHESSPDI SHFERSKQVS SVNEEDFVRL KQQISDHISQ SCGSGQMKMF QEVSAADAFG PGTEGQVERF ETVGMEAATD EGMPKSYLPQ TVRQGGYMPQ
Target Information
The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. Activation depends on cytokine binding to receptors. vIL6, encoded by Kaposi sarcoma-associated herpesvirus, can bypass IL6R and directly activate this protein. Knockout studies in mice indicate a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-109856_GP130_P40189-1_Rabbit.svg, PA5-109856_GP130_P40189-1_Rabbit_PDP.jpeg)
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