Thermo Fisher Scientific GP130 Polyclonal Antibody

Applications

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
PSISSSDENE SSQNTSSTVQ YSTVVHSGYR HQVPSVQVFS RSESTQPLLD SEERPEDLQL VDHVDGGDGI LPRQQYFKQN CSQHESSPDI SHFERSKQVS SVNEEDFVRL KQQISDHISQ SCGSGQMKMF QEVSAADAFG PGTEGQVERF ETVGMEAATD EGMPKSYLPQ TVRQGGYMPQ

Target Information

The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. Activation depends on cytokine binding to receptors. vIL6, encoded by Kaposi sarcoma-associated herpesvirus, can bypass IL6R and directly activate this protein. Knockout studies in mice indicate a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 파일: PA5-109856_GP130_P40189-1_Rabbit.svg, PA5-109856_GP130_P40189-1_Rabbit_PDP.jpeg)