Thermo Fisher Scientific Phospho-EGFR (Tyr1068) Recombinant Rabbit Monoclonal Antibody (EGFRY1068-E5), APC

Applications

• Flow Cytometry (Flow): 5 µL / 1×10⁶ cells

Product Specifications

Additional Formats

• Unconjugated (MA5-36965)
• FITC (MA5-36967)
• PE (MA5-36966)
• Custom conjugation available upon request

Product Specific Information

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select optimal candidates for production.

Advantages:

• Enhanced specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broad immunoreactivity due to rabbit immune repertoire

Target Information

EGFR (epidermal growth factor receptor) is a receptor tyrosine kinase that mediates signaling in response to various growth factors. Overexpression of EGFR is associated with multiple cancer types and serves as a therapeutic target for biological and small molecule drugs.
EGFR is encoded on human chromosome 7 and belongs to the HER/ErbB family (ErbB2, ErbB3, ErbB4). Ligand binding (e.g., EGF, TGF-α) induces receptor dimerization and autophosphorylation at tyrosine residues, activating downstream signaling pathways.
Overexpression is observed in cancers of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, and in squamous cell carcinoma.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

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