Thermo Fisher Scientific Phospho-ATF2 (Thr71) Recombinant Rabbit Monoclonal Antibody (ATF2T71-G3)

Applications

Western Blot (WB)

• Assay-dependent

Flow Cytometry (Flow)

• 1–1,000 ng/mL

Product Specifications

Additional Formats

• APC
• FITC
• PE
• Request custom conjugation

Product Specific Information

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. These systems clone antibody DNA sequences from immunoreactive rabbits, and individual clones are screened for optimal performance.
Advantages include:

• Improved specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulations
• Broad immunoreactivity due to the rabbit immune repertoire

Target Information

The transcription factor ATF-2 (also called CRE-BP1) binds to both AP-1 and CRE DNA response elements and belongs to the ATF/CREB family of leucine zipper proteins.
ATF-2:

• Interacts with viral oncoproteins and cellular tumor suppressors
• Is a target of SAPK/JNK and p38 MAP kinase signaling pathways
• Is activated by cellular stress (e.g., genotoxic agents, cytokines, UV)
• Undergoes phosphorylation at Thr69 and Thr71, mediated by SAPK and p38 MAPK

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.