
Thermo Fisher Scientific NT3 Monoclonal Antibody (OTI3D4), TrueMAB
NT3 단백질을 인식하는 마우스 단일클론 항체로, Western blot 및 IHC에 적합합니다. 인간 NT3(AA139-257) 재조합 단백질을 면역원으로 제작되었으며, 무보존제 PBS 버퍼에 동결건조 형태로 제공됩니다. 신경영양인자 연구용으로 권장됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:5,000–1:10,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D4 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 139–257 of human NT3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The NT3 protein belongs to the neurotrophin family, which regulates survival and differentiation of mammalian neurons. It is closely related to nerve growth factor and brain-derived neurotrophic factor. NT3 may contribute to neuronal development in embryos and maintenance of the adult nervous system. NTF3-deficient mice exhibit severe limb movement defects. The mature peptide sequence is conserved across mammals including human, pig, rat, and mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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