Thermo Fisher Scientific NT3 Monoclonal Antibody (OTI5A2), TrueMAB
인간 NT3 단백질을 표적으로 하는 마우스 단클론 항체로, Western blot 및 파라핀 조직 면역조직화학에 적합합니다. 무보존제, 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능합니다. 신경영양인자 연구용으로 최적화된 TrueMAB 제품입니다.
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Applications
- Western Blot (WB): 1:5,000
- Immunohistochemistry (Paraffin) (IHC-P): 1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5A2 |
| Immunogen | Recombinant protein expressed in E. coli corresponding to amino acids 139–257 of human NT3 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform additional desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The NT3 protein (Neurotrophin-3) is a member of the neurotrophin family that regulates survival and differentiation of mammalian neurons. It is closely related to nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF). NT3 may play roles in maintaining the adult nervous system and in embryonic neuronal development.
NTF3-deficient mice show severe limb movement defects. The mature peptide sequence is identical across mammals including human, pig, rat, and mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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