Thermo Fisher Scientific DNAI1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 350-699 of human DNAI1 (NP_0362761) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DNAI1,uniProtId:Q9UI46-1,ncbiNodeId:9606,antigenRange:350-699,antigenLength:699,antigenImageFileName:PA5-88366_DNAI1_Q9UI46-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88366_DNAI1_Q9UI46-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.56 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804861

Product Specific Information

Immunogen sequence: VGYGSYDFMK QSRGMLLLYS LKNPSFPEYM FSSNSGVMCL DIHVDHPYLV AVGHYDGNVA IYNLKKPHSQ PSFCSSAKSG KHSDPVWQVK WQKDDMDQNL NFFSVSSDGR IVSWTLVKRK LVHIDVIKLK VEGSTTEVPE GLQLHPVGCG TAFDFHKEID YMFLVGTEEG KIYKCSKSYS SQFLDTYDAH NMSVDTVSWN PYHTKVFMSC SSDWTVKIWD HTIKTPMFIY DLNSAVGDVA WAPYSSTVFA AVTTDGKAHI FDLAINKYEA ICNQPVAAKK NRLTHVQFNL IHPIIIVGDD RGHIISLKLS PNLRKMPKEK KGQEVQKGPA VEIAKLDKLL NLVREVKIKT; Positive Samples: HeLa, SKOV3, U-87MG, Mouse kidney; Cellular Location: Cytoplasm, cilium axoneme, cytoskeleton

Target Information

Eukaryotic cells rely on actin and microtubule-based protein motors to generate intracellular movements. These protein motors contain specialized domains that hydrolyze ATP to produce force and movement along a cytoskeletal polymer (actin in the case of myosin family and microtubules in the case of the kinesin family and dyneins). Dynein has been implicated in cytoplasmic motile functions, including chromosomal movement, retrograde organelle and axonal transport, the endocytic pathway, and the organization of the Golgi apparatus. In all cell types, dynein has the same basic structures and is composed of two or three distinct heavy chains (~450 kDa), three intermediate chains (70-125 kDa), and at least four light chains (15-25 kDa).

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.