Thermo Fisher Scientific NALP11 Polyclonal Antibody
Thermo Fisher Scientific의 NALP11 Polyclonal Antibody는 인간 NALP11 단백질을 인식하는 토끼 유래 다클론 항체로, Western blot과 ELISA에 적합합니다. 고순도 친화 크로마토그래피 정제, 액상 형태, -20°C 보관 조건으로 안정적입니다.
- 카탈로그번호
- PA588368
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 420–600 of human NLRP11 (NP_6594442) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.26 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804863 |
Product Specific Information
Immunogen sequence:
VGFTEADVSV LQAANILLPS NTHKDRYKFI HLNVQEFCTA IAFLMAVPNY LIPSGSREYK EKREQYSDFN QVFTFIFGLL NANRRKILET SFGYQLPMVD SFKWYSVGYM KHLDRDPEKL THHMPLFYCL YENREEEFVK TIVDALMEVT VYLQSDKDMM VSLYCLDYCC HLRTLKLSVQ R
Positive Samples: 293T
Target Information
NALP11 is a 1033 amino acid cytoplasmic protein belonging to the NLRP family, containing a DAPIN domain, six leucine-rich repeats (LRR), and a NACHT domain. It is implicated in inflammation processes and the activation of proinflammatory caspases such as CASP1 through inflammasome formation. The DAPIN domain is essential for suppression of NF-kappa B activation induced by TNF and for IL-1B secretion in collaboration with Caspase-1. It also interacts with PYCARD.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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