Thermo Fisher Scientific SART3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 664-963 of human SART3 (NP_0555211) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SART3,uniProtId:Q15020-1,ncbiNodeId:9606,antigenRange:664-963,antigenLength:963,antigenImageFileName:PA5-88362_SART3_Q15020-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88362_SART3_Q15020-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.42 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804858

Product Specific Information

Immunogen sequence: AGPAGKCAAV DVEPPSKQKE KAASLKRDMP KVLHDSSKDS ITVFVSNLPY SMQEPDTKLR PLFEACGEVV QIRPIFSNRG DFRGYCYVEF KEEKSALQAL EMDRKSVEGR PMFVSPCVDK SKNPDFKVFR YSTSLEKHKL FISGLPFSCT KEELEEICKA HGTVKDLRLV TNRAGKPKGL AYVEYENESQ ASQAVMKMDG MTIKENIIKV AISNPPQRKV PEKPETRKAP GGPMLLPQTY GARGKGRTQL SLLPRALQRP SAAAPQAENG PAAAPAVAAP AATEAPKMSN ADFAKLFLRK; Positive Samples: U-87MG, A-431, HeLa, HepG2, Jurkat; Cellular Location: Cajal body, Cytoplasm, Nucleus, Nucleus speckle, nucleoplasm

Target Information

The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.