Thermo Fisher Scientific MYO7A Polyclonal Antibody
MYO7A 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 IHC 등 다양한 응용에 사용 가능. Mouse와 Rat 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. PBS+BSA 완충액에 보관되며 -20°C에서 안정적.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 4 µg/mL | View 3 publications |
| Immunohistochemistry (IHC) | - | View 10 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | - | View 1 publication |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | - | View 2 publications |
| Immunocytochemistry (ICC/IF) | 2 µg/mL | View 3 publications |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic Peptide: S(16) G Q E F D V P I G A V V K L C(31) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 1 mg/mL BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2235704 |
Product Specific Information
PA1-936 detects myosin VIIa from mouse tissues as well as recombinant protein.
It has been successfully used in Western blot procedures, detecting an ~220 kDa protein representing myosin VIIa from mouse testes preparations.
This antibody also detects recombinant mouse myosin VIIa overexpressed in Sf9 insect cell lysate.
The immunizing peptide corresponds to amino acid residues 16–31 from mouse myosin VIIa, which is completely conserved in mouse, porcine, and human myosin VIIa.
The immunizing peptide (Cat. # PEP-045) is available for use in neutralization and control experiments.
Target Information
Myosin VIIa is a member of the myosin superfamily of actin-based motor proteins.
Defects in the myosin VIIa gene cause hearing impairment in shaker-1 (sh1) mice and Usher syndrome IB in humans.
Usher syndrome combines congenital deafness, vestibular dysfunction, and retinitis pigmentosa, being the most common form of combined deafness and blindness.
Myosin VIIa protein features include an ATP-binding N-terminal motor domain, a central region with five IQ motifs, and a C-terminal domain containing three MyTH4 and talin-like homology regions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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