Thermo Fisher Scientific CNTF Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

PA1-9521 detects CNTF in human, mouse, and rat samples.
It has been successfully used in Western blot, ELISA, and immunohistochemistry procedures.
By Western blot, PA1-9521 detects a 23 kDa protein representing CNTF.
The immunogen is a synthetic peptide based on the human CNTF protein.
Store at 4°C for up to 1 week, and -20°C as undiluted liquid for long-term storage.

Target Information

The CNTF protein is a polypeptide hormone primarily active in the nervous system, promoting neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. It acts as a potent survival factor for neurons and oligodendrocytes and may help reduce tissue destruction during inflammatory attacks.
A mutation in this gene can lead to ciliary neurotrophic factor deficiency, though it is not directly linked to neurologic disease.
A read-through transcript variant composed of ZFP91 and CNTF sequences has been identified but is thought to be non-coding. Similar read-through transcription has also been observed in mouse.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.