Thermo Fisher Scientific BDNF Polyclonal Antibody
인간 및 생쥐 시료에서 BDNF 검출용 폴리클로날 항체. ELISA에 적합하며 IgY 정제된 액상 형태. 장기 보관 시 -20°C에서 냉동 보관 권장. 신경세포 생존 및 분화 연구에 유용.
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Thermo Fisher Scientific BDNF Polyclonal Antibody
Applications
- ELISA
Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Chicken / IgY |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Two peptides from human BDNF that were mixed |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | IgY fraction |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2064202 |
Product Specific Information
PA1-9522 detects BDNF in human and mouse samples.
PA1-9522 has been successfully used in ELISA procedures.
PA1-9522 immunogen is two peptides from human BDNF that were mixed.
Target Information
BDNF (Brain-Derived Neurotrophic Factor) is a member of the neurotrophin family. It is synthesized as pre-proBDNF, followed by cleavage to proBDNF. Further processing generates the mature, 14 kDa protein, and both pro-BDNF and mature forms are biologically active.
BDNF is widely expressed in the central nervous system and acts in an autocrine and paracrine manner on several classes of neurons. It signals mainly through the tyrosine kinase receptor TrkB, and also binds to the lower-affinity receptor p75-NTR.
BDNF promotes neuronal survival and differentiation and plays a critical role in memory formation and synaptic regulation. Its expression is reduced in Alzheimer’s and Huntington’s disease and may be involved in stress response and mood disorder biology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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