Thermo Fisher Scientific H-cadherin Polyclonal Antibody
H-cadherin 단백질을 인식하는 Thermo Fisher Scientific의 Goat Polyclonal Antibody로, WB, IHC, ICC/IF, Flow Cytometry 등에 사용 가능. 인간 시료 반응성, 항원 친화 크로마토그래피 정제, 무보존제 PBS 버퍼 제공. 연구용으로만 사용.
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Thermo Fisher Scientific H-cadherin Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–10 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5–15 µg/mL |
| Immunocytochemistry (ICC/IF) | 5–15 µg/mL |
| Flow Cytometry (Flow) | 2.5 µg per million cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human Cadherin-13 (Glu23–Ala692) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608495 |
Product Specific Information
In direct ELISAs, approximately 100% cross-reactivity with recombinant mouse Cadherin-13 is observed.
Less than 10% cross-reactivity with recombinant human N-Cadherin, and less than 2% with rhCadherin-8, rhCadherin-11, rhCadherin-17, rhE-Cadherin, rhP-Cadherin, rhVE-Cadherin, and rhR-Cadherin.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, catalyzing removal of the 3′ trailer from precursor tRNAs.
It interacts with activated Smad2 and its nuclear partner forkhead box H1 (FAST-1). Reduced expression can suppress TGF-beta induced growth arrest.
Mutations in this gene increase prostate cancer risk. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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