Thermo Fisher Scientific HNF4A Monoclonal Antibody (OTI8B8), TrueMAB
HNF4A 단백질을 인식하는 Mouse IgG2a 단일클론 항체로 Western blot에 적합. 인간 시료에 반응하며, 보존제 없이 동결건조 형태로 제공. 재구성 및 결합 실험에 용이하며, MODY1 관련 연구에 활용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8B8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–315 of human HNF4A produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
Hepatocyte nuclear factor 4 alpha (HNF4A) is an orphan nuclear receptor expressed in the liver, kidney, intestine, and pancreas.
Mutations in HNF4A are associated with maturity-onset diabetes of the young type 1 (MODY1).
HNF4A binds DNA as a homodimer and has up to nine isoforms (HNF4A1–HNF4A9) generated by alternative splicing.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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