Thermo Fisher Scientific HPV Type 16 E7 Recombinant Mouse Monoclonal Antibody (Nb12)
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 재고 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
MA554353 | - | Thermo Fisher Scientific MA554353 HPV Type 16 E7 Recombinant Mouse Monoclonal Antibody (Nb12) 100 ug pk | 재고문의 | pk | 0원 | - | 0원 |
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Applications
Tested Dilution
Publications
Western Blot (WB)
Assay-dependent
ELISA (ELISA)
Assay-dependent
Neutralization (Neu)
Assay-dependent
Product Specifications
Species Reactivity
Virus
Host/Isotype
Mouse / VHH-mFc
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
Nb12
Immunogen
Recombinant HPV 16 E7/Protein E7.
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A/G
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Specific Information
Compatible with Direct ELISA
Target Information
The HPV E7 proteins are small (HPV16 E7 comprising 98 amino acids, 15kDa), zinc binding phosphoproteins which are localised in the nucleus. They are structurally and functionally similar to the E1A protein of subgenus C adenoviruses. The first 16 amino-terminal amino acids of HPV16 E7 contain a region homologous to a segment of the conserved region 1 (CR1) of the E1A protein of subgenus C adenoviruses. The next domain, up to amino acid 37, is homologous to the entire region 2 (CR2) of E1A. Genetic studies have established that these domains are required for cell transformation in vitro, suggesting similarities in the mechanism of transformation by these viruses. The CR2 homology region contains the LXCXE motif (residues 22-26) involved in binding to the tumour suppressor protein pRb.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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