Thermo Fisher Scientific RSV Fusion Protein VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1036)

Applications

• ELISA (ELISA): Assay-dependent

Product Specifications

Product Specific Information

• Compatible with Direct ELISA

Target Information

Human respiratory syncytial virus (RSV) is a member of the Paramyxoviridae family, subfamily Pneumovirinae, that causes common respiratory tract infections such as measles and mumps.
Its genome consists of single-stranded, negative-sense RNA that encodes three envelope glycoproteins:

• A small hydrophobic (SH) protein of unknown function
• A major glycoprotein (G) known as the attachment protein
• A fusion (F) protein

The 63 kD RSV fusion protein of the RSS 2 strain (subtype A) directs fusion of viral and cellular membranes, resulting in viral penetration, and can also direct fusion of infected cells with adjoining cells, forming syncytia or multinucleated giant cells.
Its name derives from the fact that F proteins on the surface of the virus cause membranes of nearby cells to merge, forming syncytia.

While RSV typically produces mild symptoms in adults, it is one of the leading causes of lower respiratory tract infections and hospital visits during infancy and childhood.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.