
Thermo Fisher Scientific IGFBP3 Monoclonal Antibody (OTI16B1), TrueMAB
IGFBP3 단백질을 인식하는 마우스 단일클론 항체로 Western blot에 적합. 인간 시료 반응성. 동결건조 형태로 공급되며 PBS, trehalose buffer에 재구성 가능. 연구용으로 IGF 관련 신호전달 연구에 활용.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI16B1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 28–297 of human IGFBP3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, an additional desalting step is recommended (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
IGFBP3 belongs to the insulin-like growth factor binding protein (IGFBP) family. The encoded protein contains both an IGFBP domain and a thyroglobulin type-I domain. It forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either IGF-I or IGF-II, which circulates in plasma, prolonging IGF half-life and modulating receptor interactions.
Multiple isoforms exist due to alternative splicing.
Diseases associated with IGFBP3 include Insulin-Like Growth Factor I and Acid-Labile Subunit Deficiency.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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