Thermo Fisher Scientific Human IgG4 (S228P) Recombinant Isotype Control (HyHEL-10)
Human IgG4 (S228P) recombinant isotype control for flow cytometry and immunological assays. Produced in CHO cells, purified via Protein A/G. Unconjugated format for flexible labeling. Ideal for antibody validation and assay control.
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- MA555104
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- pk
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Applications
- Flow Cytometry (Flow): Assay-dependent dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Human / IgG4 |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Isotype Control |
| Clone | HyHEL-10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Target Information
Human IgG4 (human immunoglobulin G4) is a subclass of human IgG antibodies produced by the immune system in response to antigens. It is the least abundant IgG subclass in blood and plays a minor role in pathogen defense. IgG4 binds to specific antigens, promoting their clearance through mechanisms such as phagocytosis and complement activation. Additionally, IgG4 contributes to immune tolerance and suppression of inflammation.
Human IgG4 is widely used in research for studying immune responses and developing diagnostic or therapeutic approaches for infectious and autoimmune diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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