Thermo Fisher Scientific CACNA1A Polyclonal Antibody
CACNA1A 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 IHC에 적합하며 인간, 마우스, 랫트 반응성. 합성 펩타이드 항원 기반, 동결건조 형태로 제공. 연구용으로 안정적 장기 보관 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | – |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | – |
| Miscellaneous (PubMed) | – | View 1 publication |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide from mouse CACNA1A conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide is homologous in rat and human.
- Specificity: CACNA1A.
Target Information
Voltage-dependent calcium channels mediate calcium ion entry into excitable cells and participate in calcium-dependent processes such as muscle contraction, hormone/neurotransmitter release, and gene expression. These channels consist of alpha-1, beta, alpha-2/delta, and gamma subunits, with alpha-1 forming the pore and determining channel type characteristics.
The CACNA1A gene encodes the alpha-1A subunit, predominantly expressed in neuronal tissue. Mutations are linked to familial hemiplegic migraine and episodic ataxia type 2. Polymorphic variations with n-repeats exist; expansions in coding regions (21–28 repeats) are associated with spinocerebellar ataxia type 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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